diff --git a/.changeset/small-knives-sparkle.md b/.changeset/small-knives-sparkle.md
new file mode 100644
index 000000000..e257d5e97
--- /dev/null
+++ b/.changeset/small-knives-sparkle.md
@@ -0,0 +1,5 @@
+---
+'astro': patch
+---
+
+Throw better error when a dynamic endpoint without additional extensions is prerendered with `undefined` params.
diff --git a/packages/astro/src/core/errors/errors-data.ts b/packages/astro/src/core/errors/errors-data.ts
index 5e0b9a34d..760cade33 100644
--- a/packages/astro/src/core/errors/errors-data.ts
+++ b/packages/astro/src/core/errors/errors-data.ts
@@ -530,6 +530,27 @@ See https://docs.astro.build/en/guides/server-side-rendering/ for more informati
 			)} are supported for optimization.`,
 		hint: "If you do not need optimization, using an `img` tag directly instead of the `Image` component might be what you're looking for.",
 	},
+	/**
+	 * @docs
+	 * @see
+	 * - [`getStaticPaths()`](https://docs.astro.build/en/reference/api-reference/#getstaticpaths)
+	 * - [`params`](https://docs.astro.build/en/reference/api-reference/#params)
+	 * @description
+	 * The endpoint is prerendered with an `undefined` param so the generated path will collide with another route.
+	 *
+	 * If you cannot prevent passing `undefined`, then an additional extension can be added to the endpoint file name to generate the file with a different name. For example, renaming `pages/api/[slug].ts` to `pages/api/[slug].json.ts`.
+	 */
+	PrerenderDynamicEndpointPathCollide: {
+		title: 'Prerendered dynamic endpoint has path collision.',
+		code: 3026,
+		message: (pathname: string) =>
+			`Could not render \`${pathname}\` with an \`undefined\` param as the generated path will collide during prerendering. ` +
+			`Prevent passing \`undefined\` as \`params\` for the endpoint's \`getStaticPaths()\` function, ` +
+			`or add an additional extension to the endpoint's filename.`,
+		hint: (filename: string) =>
+			`Rename \`${filename}\` to \`${filename.replace(/\.(js|ts)/, (m) => `.json` + m)}\``,
+	},
+
 	// No headings here, that way Vite errors are merged with Astro ones in the docs, which makes more sense to users.
 	// Vite Errors - 4xxx
 	/**
diff --git a/packages/astro/src/core/render/core.ts b/packages/astro/src/core/render/core.ts
index f3b8e2866..d072c85b4 100644
--- a/packages/astro/src/core/render/core.ts
+++ b/packages/astro/src/core/render/core.ts
@@ -35,6 +35,27 @@ export async function getParamsAndProps(
 			const paramsMatch = route.pattern.exec(pathname);
 			if (paramsMatch) {
 				params = getParams(route.params)(paramsMatch);
+
+				// If we have an endpoint at `src/pages/api/[slug].ts` that's prerendered, and the `slug`
+				// is `undefined`, throw an error as we can't generate the `/api` file and `/api` directory
+				// at the same time. Using something like `[slug].json.ts` instead will work.
+				if (route.type === 'endpoint' && mod.getStaticPaths) {
+					const lastSegment = route.segments[route.segments.length - 1];
+					const paramValues = Object.values(params);
+					const lastParam = paramValues[paramValues.length - 1];
+					// Check last segment is solely `[slug]` or `[...slug]` case (dynamic). Make sure it's not
+					// `foo[slug].js` by checking segment length === 1. Also check here if that param is undefined.
+					if (lastSegment.length === 1 && lastSegment[0].dynamic && lastParam === undefined) {
+						throw new AstroError({
+							...AstroErrorData.PrerenderDynamicEndpointPathCollide,
+							message: AstroErrorData.PrerenderDynamicEndpointPathCollide.message(route.route),
+							hint: AstroErrorData.PrerenderDynamicEndpointPathCollide.hint(route.component),
+							location: {
+								file: route.component,
+							},
+						});
+					}
+				}
 			}
 		}
 		let routeCacheEntry = routeCache.get(route);
diff --git a/packages/astro/test/dynamic-endpoint-collision.js b/packages/astro/test/dynamic-endpoint-collision.js
new file mode 100644
index 000000000..b8620568a
--- /dev/null
+++ b/packages/astro/test/dynamic-endpoint-collision.js
@@ -0,0 +1,52 @@
+import { expect } from 'chai';
+import { load as cheerioLoad } from 'cheerio';
+import { loadFixture } from './test-utils.js';
+
+describe('Dynamic endpoint collision', () => {
+	describe('build', () => {
+		let fixture;
+		let errorMsg;
+		before(async () => {
+			fixture = await loadFixture({
+				root: './fixtures/dynamic-endpoint-collision/',
+			});
+			try {
+				await fixture.build();
+			} catch (error) {
+				errorMsg = error;
+			}
+		});
+
+		it('throw error when dynamic endpoint has path collision', async () => {
+			expect(errorMsg.errorCode).to.eq(3026);
+		});
+	});
+
+	describe('dev', () => {
+		let fixture;
+		let devServer;
+
+		before(async () => {
+			fixture = await loadFixture({
+				root: './fixtures/dynamic-endpoint-collision/',
+			});
+
+			devServer = await fixture.startDevServer();
+		});
+
+		after(async () => {
+			await devServer.stop();
+		});
+
+		it('throw error when dynamic endpoint has path collision', async () => {
+			const html = await fixture.fetch('/api/catch').then((res) => res.text());
+			const $ = cheerioLoad(html);
+			expect($('title').text()).to.equal('PrerenderDynamicEndpointPathCollide');
+		});
+
+		it("don't throw error when dynamic endpoint doesn't load the colliding path", async () => {
+			const res = await fixture.fetch('/api/catch/one').then((r) => r.text());
+			expect(res).to.equal('{"slug":"one"}');
+		});
+	});
+});
diff --git a/packages/astro/test/fixtures/dynamic-endpoint-collision/astro.config.mjs b/packages/astro/test/fixtures/dynamic-endpoint-collision/astro.config.mjs
new file mode 100644
index 000000000..0c1afccde
--- /dev/null
+++ b/packages/astro/test/fixtures/dynamic-endpoint-collision/astro.config.mjs
@@ -0,0 +1,7 @@
+import { defineConfig } from 'astro/config';
+
+
+// https://astro.build/config
+export default defineConfig({
+
+});
diff --git a/packages/astro/test/fixtures/dynamic-endpoint-collision/package.json b/packages/astro/test/fixtures/dynamic-endpoint-collision/package.json
new file mode 100644
index 000000000..7a40aff87
--- /dev/null
+++ b/packages/astro/test/fixtures/dynamic-endpoint-collision/package.json
@@ -0,0 +1,8 @@
+{
+  "name": "@test/dynamic-endpoint-collision",
+  "version": "0.0.0",
+  "private": true,
+  "dependencies": {
+    "astro": "workspace:*"
+  }
+}
diff --git a/packages/astro/test/fixtures/dynamic-endpoint-collision/src/pages/api/catch/[...slug].ts b/packages/astro/test/fixtures/dynamic-endpoint-collision/src/pages/api/catch/[...slug].ts
new file mode 100644
index 000000000..8f64c2401
--- /dev/null
+++ b/packages/astro/test/fixtures/dynamic-endpoint-collision/src/pages/api/catch/[...slug].ts
@@ -0,0 +1,15 @@
+import type { APIRoute } from "astro";
+
+const slugs = ["one", undefined];
+
+export const get: APIRoute = ({ params }) => {
+  return {
+    body: JSON.stringify({
+      slug: params.slug || "index",
+    }),
+  };
+};
+
+export function getStaticPaths() {
+  return slugs.map((u) => ({ params: { slug: u } }));
+}
diff --git a/packages/astro/test/fixtures/unused-slot/src/components/Card.astro b/packages/astro/test/fixtures/unused-slot/src/components/Card.astro
index 61fafb04c..c77e31672 100644
--- a/packages/astro/test/fixtures/unused-slot/src/components/Card.astro
+++ b/packages/astro/test/fixtures/unused-slot/src/components/Card.astro
@@ -5,7 +5,6 @@ export interface Props {
     href: string,
 }
 const {href, title, body} = Astro.props;
-debugger;
 ---
 <li class="link-card">
     <a href={href}>
diff --git a/pnpm-lock.yaml b/pnpm-lock.yaml
index b8547b9a0..6e52dbc5b 100644
--- a/pnpm-lock.yaml
+++ b/pnpm-lock.yaml
@@ -1971,6 +1971,12 @@ importers:
     dependencies:
       astro: link:../../..
 
+  packages/astro/test/fixtures/dynamic-endpoint-collision:
+    specifiers:
+      astro: workspace:*
+    dependencies:
+      astro: link:../../..
+
   packages/astro/test/fixtures/dynamic-route-build-file:
     specifiers:
       astro: workspace:*