diff --git a/.changeset/pink-ghosts-end.md b/.changeset/pink-ghosts-end.md
new file mode 100644
index 000000000..7eaa13010
--- /dev/null
+++ b/.changeset/pink-ghosts-end.md
@@ -0,0 +1,5 @@
+---
+'astro': patch
+---
+
+fix: build fail upon have 'process.env' in \*.md file.
diff --git a/packages/astro/src/vite-plugin-utils/index.ts b/packages/astro/src/vite-plugin-utils/index.ts
index fb10de1ee..b9cc60576 100644
--- a/packages/astro/src/vite-plugin-utils/index.ts
+++ b/packages/astro/src/vite-plugin-utils/index.ts
@@ -14,7 +14,9 @@ import { viteID } from '../core/util.js';
  * in our JS representation of modules like Markdown
  */
 export function escapeViteEnvReferences(code: string) {
-	return code.replace(/import\.meta\.env/g, 'import\\u002Emeta.env');
+	return code
+		.replace(/import\.meta\.env/g, 'import\\u002Emeta.env')
+		.replace(/process\.env/g, 'process\\u002Eenv');
 }
 
 export function getFileInfo(id: string, config: AstroConfig) {